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Of the 105 primary statistical areas in the U.S. The wider San Jose–San Francisco–Oakland, CA Combined Statistical Area is the fifth most populous, with 9.6 million residents, and the third-largest by economic output, with a GDP of $1.09 trillion in 2019. San Francisco anchors the 12th most populous metropolitan statistical area in the United States with 4.7 million residents, and the fourth-largest by economic output, with a GDP of $592 billion in 2019. As of 2018, the metropolitan area, with 6.7 million residents, ranked 6th by GDP ($884 billion) and first by GDP per capita ($131,538) across the OECD group of countries, ahead of global cities like London, Singapore, or Hong Kong.
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San Francisco and the surrounding San Francisco Bay Area are a global center of economic activity and the arts and sciences, spurred by leading universities, high-tech, healthcare, FIRE, and professional services sectors. Colloquial nicknames for San Francisco include SF, The City, and Frisco. cities proper with more than 100,000 residents, San Francisco was ranked first by per capita income (at $133,856 ) and fifth by aggregate income as of 2019. county, behind only four of the five New York City boroughs.
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city after New York City, and the fifth most densely populated U.S. It covers a land area of 46.9 square miles (121 square kilometers), at the end of the San Francisco Peninsula, making it the second most densely populated large U.S. The city proper is the 17th most populous in the United States, and the fourth most populous in California, with 815,201 residents as of 2021. San Francisco ( / ˌ s æ n f r ə n ˈ s ɪ s k oʊ/ Spanish for " Saint Francis"), officially the City and County of San Francisco, is a commercial and cultural center in the northern region of the U.S.